Topic of Research Seminar: Development of Novel Diagnostic Angiographic Catheter, Evaluation of Its Efficacy, Precision, And Ease of Application
Abstract: Cardiovascular diseases cause approximately one-third of deaths worldwide. Keeping in mind the unceasingly escalating prevalence of coronary disease worldwide, the mortality rate is also expected to rise with a staggering increase in healthcare costs. Angiography is the gold standard for diagnosing coronary blockages and suggesting therapeutics. The braided reinforced shaft is the common catheter construction material, but recent research focuses on developing laser-cut reinforced shaft catheters. The purpose of this research is to develop and analyze the laser-cut reinforced shaft-based angiographic catheters to assess their potential usage for coronary angiographic procedures. A novel ‘I’ hollow geometry has been used for the fabrication of reinforced shafts. Stainless Steel 304 was selected as a material for fabricating a laser-cut reinforced shaft and PTFE for inner lumen, and PEBAX for jacketing because of their good biocompatibility and low coefficient of friction. This study analyses and reports the design, performance, and behavior of laser-cut reinforced shaft catheters. The catheter’s performance and arterial forces’ endurance nature have been mapped out by evaluating pushability and selective bench tests. An attempt has been made to compare these characteristics with commercially available amides and urethane-based catheters through ISO-10555-1:2013. The ‘I’ geometry of laser-cut reinforced shaft catheter differed from braided catheters based on ovality retention, enhanced flexural rigidity, and pushability; the pushability force analysis results prove that laser-
cut reinforced shaft catheter exerts a minimal resistive force (625g) which is approximately 1/3rd times less than the braided catheter. This study also endeavored to manufacture a significantly lower wall thickness for reinforced angiographic catheters. Based on this extensive in-vitro assessment, it has been concluded that laser-cut reinforced shaft catheter performed better in advancement force and flexibility than the braided angiographic catheter. In performance evaluation, the laser-cut reinforced shaft catheter has outperformed 16 and 32 wires commercially available braided catheters, exhibiting an exceptionally minimal advancement force of 6 N.
Subject field of Topic: Cardiovascular Device
Name of Speaker: Hafsa Inam
Professional Rank of Speaker: PhD Student
University Email of Speaker: email@example.com
Affiliation of Speaker: NUST School of Mechanical and Manufacturing Engineering (NUST-SMME)
Date and Venue: October 10, 2022, 1700 – 1630 hrs, NUST School of Mechanical and Manufacturing Engineering (NUST-SMME), NUST Islamabad Campus.