Topic of Research Seminar: Synthesis and Biological Evaluation of New Triphenylamine-Linked Pyridine and Thiazole Analogues as Anticancer Agents

Abstract: After cardiovascular disease cancer remains one of the leading causes of mortality worldwide, characterized by uncontrolled cell proliferation and metastasis. Effective treatment strategies are crucial for improving patient outcomes and quality of life. Current medicinal treatments encompass a range of approaches, including surgery, radiation therapy, chemotherapy, targeted therapy, immunotherapy, and hormonal therapy. In this regard, heterocyclic compounds play a crucial role in the advancement of cancer therapeutics particularly emphasizing nitrogen-containing compounds, which constitute a majority of FDA-approved anticancer agents, serving as foundational structures in a significant proportion of currently approved anticancer drugs. The structural versatility of these compounds allows for targeted interactions with various biological pathways involved in cancer progression. Continued investment in this area is essential for overcoming current treatment limitations and improving patient outcomes.

Subject Field of Topic: Chemistry

Name of Speaker: Ms. Ghazala Razaq Abbasi

Professorial Rank of Speaker: PhD Scholar (Chemistry Dpt.), School of Natural Sciences (SNS), NUST

Email of Speaker: [email protected]

Affiliation of Speaker: School of Natural Sciences (SNS), NUST

Date and Venue: (Thursday) 14 November 2024, 1400 hrs, at CR #205 (New SNS Building), School of Natural Sciences (SNS), NUST Islamabad